|
KMID : 1145120160140020119
|
|
Asian Journal of Beauty and Cosmetology
2016 Volume.14 No. 2 p.119 ~ p.126
|
|
|
Anti-aging Effect of Psoraleae Fructus Extract in UVA-irradiated HaCaT Cells
|
|
Park Sun-Young
Shim Joong-Hyun
|
|
|
Abstract
|
|
|
Purpose: This research was carried out to identify the skin anti-aging effect of Psoraleae Fructus extract on HaCaT cells.
Methods: To investigate anti-aging effects of Psoraleae Fructus on HaCaT cells, we measured cell viability, mRNA expression, and hyaluronic acid secretion.
Results: In this study, we elucidated the effects of Psoraleae Fructus extract on AQP3, HAS2, KRT1, and KRT10 mRNA expression and hyaluronic acid production. Real-time RT-PCR showed that Psoraleae Fructus extract increased mRNA level of AQP3, HAS2, KRT1, and KRT10 gene and HA-ELISA assay also revealed that Psoraleae Fructus increased HA production in HaCaT cells.
Conclusion: Therefore, we successfully identified the anti-aging effect of Psoraleae Fructus extract, and this result showed that the Psoraleae Fructus extract can be a considerable potent cosmetic ingredient for skin moisturizing and anti-aging. Based on this, we anticipated further researches will study mechanisms of Psoraleae Fructus extract to develop not only cosmetics but healthcare food or medicines.
|
|
|
KEYWORD
|
|
|
Psoraleae Fructus, Hyaluronic acid, Anti-aging, AQP3, HAS2
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|